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Synthesis of the Heterocyclic Core of the GE 2270 Antibiotics and Structure Elucidation of a Major Degradation Product

โœ Scribed by Golo Heckmann; Thorsten Bach


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
105 KB
Volume
44
Category
Article
ISSN
0044-8249

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As a consequence of aggregate formation, no 'H NMR spectra of the amphiphilic antibiotic moenomycin A have been obtained previously. It was now found that the system moenomycin A-D20-C,D, after sonification yielded highly resolved 'H NMR spectra, probably due to the formation of a microemulsion. Sim