𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of the first chiral PNA monomer labelled with a Fischer-type carbene complex

✍ Scribed by Stefano Maiorana; Emanuela Licandro; Dario Perdicchia; Clara Baldoli; Barbara Vandoni; Clelia Giannini; Michele Salmain

Book ID
104422488
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
239 KB
Volume
204-205
Category
Article
ISSN
1381-1169

No coin nor oath required. For personal study only.

✦ Synopsis

The synthesis, through a cross-metathesis reaction, of the first chiral peptide nucleic acid (PNA) monomer labelled with a Fischer-type carbene complex of chromium is reported. IR analysis of the new bioconjugate shows that the Cr(CO) 4 moiety represents a suitable spectroscopic probe for diagnostic purposes.

📜 SIMILAR VOLUMES

The First Synthesis of Cyclopropanone Ac
The First Synthesis of Cyclopropanone Acetals from the Reaction of Fischer Carbene Complexes with Ketene Acetals.
✍ Siu Ling B. Wang; Daniel R. Goldberg; Xuejun Liu; Jing Su; Qi-Huang Zheng; Vince 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 26 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

First Highly Regio- and Diastereoselecti
First Highly Regio- and Diastereoselective [3+2] Cycloaddition of Chiral Nonracemic Fischer Carbene Complexes with Azomethine Ylides: An Enantioselective Synthesis of (+)-Rolipram
✍ José Barluenga; Manuel A. Fernández-Rodríguez; Enrique Aguilar; Félix Fernández- 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 213 KB 👁 2 views

A new procedure for the synthesis of 1,3,4-trisubstituted and 1,4-disubstituted pyrrolidin-2-one derivatives in an enantioselective fashion is reported. The 1,3-dipolar cycloaddition of (AE)menthol and (À)-8-phenylmenthol derived Fischer alkoxy alkenyl carbene complexes with in situ generated functi

First highly regio- and diastereoselecti
First highly regio- and diastereoselective synthesis of Δ2-pyrazolines by [3+2] cycloaddition of chiral non-racemic Fischer carbene complexes with nitrilimines
✍ José Barluenga; Félix Fernández-Marí; Enrique Aguilar; Argimiro L Viado; Bernard 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 225 KB

3+2] Cycloaddition of Fischer carbene complexes with nitrilimines is described for the first time, The "onepot" conversion of Fischer carbenes into enantiomerically pure A2-pyrazolines with high regio-and diastereoselectivity is presented as an expeditious route to these compounds.