Synthesis of the dibenzyl ester of tert-butoxycarbonyl-L-alanyl-D-glutamic acid from racemic glutamic acid
โ Scribed by A. E. Zemlyakov; D. A. Poteev; V. Ya. Chirva
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 175 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0009-3130
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๐ SIMILAR VOLUMES
L-Glutamic acid has been converted into a separable mixture of D-amicetonoand L-rhodinono-y-lactones by a sequence involving transformation into (S)-y-carboxy-y-butyrolactone (2), conversion of 2 into the corresponding methyl ketone by the diazoketone route, and selective reduction with zinc borohyd
A stereo-and enantio-specific synthesis of the natural1 occurring cis-%hydroxy-(L)-pipecolic acid (3) is described, starting from Z-(L -glutamic the key step involves c chsation of a Y, to trans-%hydroxy-(L -pipecolic acl 3 3 rotected chlorohydrin, and also gives access acid, .