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Chiral synthesis of 5-hydroxy-(L)-pipecolic acids from (L)-glutamic acid

✍ Scribed by Patrick D Bailey; Justin S Bryans


Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
204 KB
Volume
29
Category
Article
ISSN
0040-4039

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✦ Synopsis


A stereo-and enantio-specific synthesis of the natural1 occurring cis-%hydroxy-(L)-pipecolic acid (3) is described, starting from Z-(L -glutamic the key step involves c chsation of a Y, to trans-%hydroxy-(L -pipecolic acl 3 3 rotected chlorohydrin, and also gives access acid, .


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