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Synthesis of the Diastereomers of Dethiobiotin Using the Conjugate Addition of 4-Phenyloxazolidin-2-one to a Nitroalkene

✍ Scribed by Denis Lucet; Philippe Heyse; Arnaud Gissot; Thierry Le Gall; Charles Mioskowski


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
266 KB
Volume
2000
Category
Article
ISSN
1434-193X

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Enantioselective Synthesis of Ξ±-Amino Ac
✍ Denis Lucet; StΓ©phane Sabelle; Olivier Kostelitz; Thierry Le Gall; Charles Miosk πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 376 KB πŸ‘ 1 views

The addition of the potassium salt of (R)-or (S)-4-phenyl-products were converted into Ξ±-amino acids and monosubstituted 1,2-diamines of high enantiomeric purity. 2-oxazolidinone to monosubstituted nitroalkenes proceeded with very good diastereoselectivity. Several of the addition derivatives are in