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Synthesis of the CD ring in taxol from (S)-(+)-carvone

✍ Scribed by Tony K.M Shing; Chi M Lee; Ho Y Lo


Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
86 KB
Volume
42
Category
Article
ISSN
0040-4039

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A new entry to the stereocontrolled synt
✍ J.S. Yadav; Pradip K. Sasmal πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 French βš– 189 KB

Stereocontrolled synthesis of the highly functionalized CD subunit of Taxol utilizing Diels-Alder reaction, Baeyer-Villiger oxidation of bridged keto system, stereodirected hydroboration using thexylborane and stereoselective Sharpless allylic hydroxylation as the key steps is described.