Synthetic studies towards the group A st
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Chris J Brennan; Jean-Marc Campagne
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Article
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2001
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Elsevier Science
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French
⚖ 106 KB
A synthesis of the C9-C23 subunit of the group A streptogramin antibiotics is described. The synthesis incorporates a palladium-catalysed sp-sp coupling and a catalytic asymmetric vinylogous Mukaiyama aldol reaction to induce the stereogenic centre at C14.