𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of the C1−C12 Fragment of Iriomoteolide 1a by Sequential Catalytic Asymmetric Vinylogous Aldol Reactions

✍ Scribed by Fang, Lijing; Xue, Haoran; Yang, Jiong


Book ID
127049597
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
398 KB
Volume
10
Category
Article
ISSN
1523-7060

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Stereoselective synthesis of the C1–C12
✍ Arun K. Ghosh; Hao Yuan 📂 Article 📅 2009 🏛 Elsevier Science 🌐 French ⚖ 365 KB

A stereoselective synthesis of the C 1 -C 12 segment of the potent cytotoxic macrolide, iriomoteolide 1a, has been accomplished. The key steps involve an enzymatic kinetic resolution of a b-hydroxy amide, a Pd-catalyzed cross-coupling to construct a substituted allylsilane, a highly and stereoselect