๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Synthesis of the C19 through C27 segment of okadaic acid using vinylogous urethane aldol chemistry: Part III

โœ Scribed by John W. Dankwardt; Sharon M. Dankwardt; Richard H. Schlessinger

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
282 KB
Volume
39
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis

The synthesis of the C-19 through C-27 segment of the marine natural product okadaic acid was accomplished employing a highly enantio-and diasteroselective aldol coupling reaction of a chiral vinylogous urethane lactone enolate. The remainder of the carbon skeleton of this segment was constructed by a diastereoselective y-oxygenated allylstannane addition. Formation of the tetrahydropyran ring was achieved utilizing a stereoselective electrophilic cyclization.

๐Ÿ“œ SIMILAR VOLUMES

ChemInform Abstract: Synthesis of the C1
ChemInform Abstract: Synthesis of the C19 Through C27 Segment of Okadaic Acid Using Vinylogous Urethane Aldol Chemistry. Part 3.
โœ J. W. DANKWARDT; S. M. DANKWARDT; R. H. SCHLESSINGER ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 41 KB ๐Ÿ‘ 1 views

Synthesis of the C 19 Through C 27 Segment of Okadaic Acid Using Vinylogous Urethane Aldol Chemistry. Part 3. -The approach towards the C 19 -C 27 fragment (X) of okadaic acid is accomplished employing a highly enantio-and diastereoselective aldol coupling reaction of the chiral vinylogous urethane

Synthesis of the C28 through C38 segment
Synthesis of the C28 through C38 segment of okadaic acid using vinylogous urethane aldol chemistry: Part IV
โœ John W. Dankwardt; Sharon M. Dankwardt; Richard H. Schlessinger ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 277 KB

The synthesis of the C-28 through C-38 segment of the marine natural product okadaic acid was accomplished employing a highly enantio-and diasteroselective aldol condensation reaction of a chii vinylogous urethane enolate. The stereocenter at C-29 was addressed utilizing a diastereoselective hydrobo

ChemInform Abstract: A Vinylogous Uretha
ChemInform Abstract: A Vinylogous Urethane Approach Towards the Synthesis of Okadaic Acid. Construction of the C9โ€”C18 Fragment. Part 2.
โœ S. M. DANKWARDT; J. W. DANKWARDT; R. H. SCHLESSINGER ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 39 KB ๐Ÿ‘ 1 views

A Vinylogous Urethane Approach Towards the Synthesis of Okadaic Acid. Construction of the C 9 -C 18 Fragment. Part 2. -In the approach towards the C 9 to C 18 fragment (XI), a diastereo-and enantioselective acylation-reduction sequence of a vinylogous urethane lactone silylketene acetal sets the in