A Vinylogous Urethane Approach Towards the Synthesis of Okadaic Acid. Construction of the C 9 -C 18 Fragment. Part 2. -In the approach towards the C 9 to C 18 fragment (XI), a diastereo-and enantioselective acylation-reduction sequence of a vinylogous urethane lactone silylketene acetal sets the in
A vinylogous urethane approach towards the synthesis of okadaic acid. construction of the C9-C18 Fragment. Part II
โ Scribed by Sharon M. Dankwardt; John W. Dankwardt; Richard H. Schlessinger
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 232 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
The synthesis of the C-19 through C-27 segment of the marine natural product okadaic acid was accomplished employing a highly enantio-and diasteroselective aldol coupling reaction of a chiral vinylogous urethane lactone enolate. The remainder of the carbon skeleton of this segment was constructed by
The synthesis of the C-28 through C-38 segment of the marine natural product okadaic acid was accomplished employing a highly enantio-and diasteroselective aldol condensation reaction of a chii vinylogous urethane enolate. The stereocenter at C-29 was addressed utilizing a diastereoselective hydrobo
Synthesis of the C 19 Through C 27 Segment of Okadaic Acid Using Vinylogous Urethane Aldol Chemistry. Part 3. -The approach towards the C 19 -C 27 fragment (X) of okadaic acid is accomplished employing a highly enantio-and diastereoselective aldol coupling reaction of the chiral vinylogous urethane