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Synthesis of the C16−C35 Fragment of Integramycin Using Olefin Hydroesterification as a Linchpin Reaction

✍ Scribed by Wang, Lijun; Floreancig, Paul E.


Book ID
127263294
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
83 KB
Volume
6
Category
Article
ISSN
1523-7060

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Use of Dibutyl[14C]formamide as a Formyl
✍ Jonathan Z. Ho; Charles S. Elmore; Michael A. Wallace; Dan Yao; Matthew P. Braun 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 German ⚖ 204 KB

## Abstract A simple, high‐yielding synthesis of dibutyl[^14^C]formamide ([^14^C]DBF; **1**) from ^14^CO~2~ was developed (__Scheme 1__): reaction of LiBEt~3~H and ^14^CO~2~ followed by aqueous workup gave H^14^CO~2~H in high yield. Conversion of the [^14^C]formic acid to **1** was effected by a st