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Synthesis of the 5′-Se-Thymidine Phosphoramidite and Convenient Labeling of DNA Oligonucleotide

✍ Scribed by Zhang, Wen; Huang, Zhen

Book ID
120266578
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
976 KB
Volume
13
Category
Article
ISSN
1523-7060

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A O l c 5-h b s u p h c p i m n s o w c e m s c a e d c w W d 0 1 E S L 5-Hydroxy-2'-deoxycytidirte (5-OHdC) 2 is one of the major stable "OH radicals and one-electron mediated oxidation products of 2'-deoxycytidine 1. Diflkrent studies have ahovm that the level of 2 increases substantially when DN