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Synthesis of Tetrahydro­benzothieno[2,3-d]pyrimidine and Tetrahydrobenzothieno[3,2-e­[1,2,4]triazolo[4,3-c]pyrimidine Derivatives as Potential Antimicrobial Agents

✍ Scribed by Soliman, Raafat


Book ID
120391093
Publisher
Austrian Pharmaceutical Society / sterreichische Pharmazeutische Gesellschaft
Year
2009
Tongue
English
Weight
242 KB
Volume
77
Category
Article
ISSN
0036-8709

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## Abstract The 7‐chloro‐3‐(2‐chlorobenzyl)‐ and 7‐chloro‐3‐(2‐fluorobenzyl)‐1,2,3‐triazolo[4,5‐__d__]pyrimidines (**1** and **4**), by nucleophilic replacement with some hydrazides, gave the corresponding 7‐hydrazidoderivatives (**2a‐e** and **5a‐e**). These, by heating in Dowtherm, underwent an i