𝔖 Bobbio Scriptorium
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Synthesis of taurine-13C2. A potential probe for human 13CO2 breath tests

✍ Scribed by B. D. Andresen; F. T. Davis; P. P. Toskes; C. E. King


Publisher
John Wiley and Sons
Year
1978
Tongue
French
Weight
295 KB
Volume
15
Category
Article
ISSN
0022-2135

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✦ Synopsis


The synthesis o f a 2% mixture o f taurine-l3Cz, i n nonlabelled taurine i s presented. taurine was prepared i n two steps as a new and p o t e n t i a l l y useful probe for 13C0, breath tests i n the diagnosis o f i n t e s t i n a l malabsorption. Unique analytical data are presented, including gas chromatographic and mass spectral data of a derivative of taurine, N-carbobenzyloxytaurine amide. These new results were essenti a1 for the characterization and determination o f isotopic enrichment o f the 2% labelled taurine probe. experiments w i t h t h i s stable, i s o t o p i c a l l y labelled mixture are also discussed.


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