The reaction of ethyl trimethylsilylacetate with two equivalents of a Grignard reagent in ether followed by treatment with acid gives 1,1-disubstituted ethylenes in excellent yield. The use ofghydroxysilanes in the formation of olefins has been a useful reaction in organic chemistry since the first
β¦ LIBER β¦
Synthesis of symmetrical 1,5-disubstituted granatanines
β Scribed by Ashish P. Vartak; Linda P. Dwoskin; Peter A. Crooks
- Book ID
- 104095759
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- French
- Weight
- 178 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0040-4039
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