Synthesis of sulfur-substituted phosphatidylethanolamines and inhibition of protozoan cyclopropane fatty acid synthase

✍ Scribed by Ruoxin Li; Shovan Ganguli; Robert A. Pascal Jr.

• Book ID: 104224842
• Publisher: Elsevier Science
• Year: 1993
• Tongue: French
• Weight: 289 KB
• Volume: 34
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)91774-x

✦ Synopsis

A bsrract: A phosphaddylethanolamine (1) containing two 9-thiastearyl groups was prepared by chemical synthesis.

This compound and its methylsulfonium dcrivatiw were found IO be inhibitors of the cyclopropune fatty acid synlhase from the parasidcprotozoan CMhidia fksciiulata.