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Synthesis of sulfonamides and sulfonic esters via reaction of amines and phenols with thiols using H2O2–POCl3 system

✍ Scribed by Kiumars Bahrami; Mohammad M. Khodaei; Jamshid Abbasi

Book ID
113929461
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
929 KB
Volume
68
Category
Article
ISSN
0040-4020

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A highly efficient diastereoselective one-pot synthesis of functionalized piperidines has been developed based on an aqua-compatible ZrOCl 2 Á8H 2 O catalyst via tandem reactions of aromatic aldehydes, amines, and acetoacetic esters.