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Efficient one-pot synthesis of functionalized piperidine scaffolds via ZrOCl2·8H2O catalyzed tandem reactions of aromatic aldehydes with amines and acetoacetic esters

✍ Scribed by Sarita Mishra; Rina Ghosh

Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
595 KB
Volume
52
Category
Article
ISSN
0040-4039

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✦ Synopsis

A highly efficient diastereoselective one-pot synthesis of functionalized piperidines has been developed based on an aqua-compatible ZrOCl 2 Á8H 2 O catalyst via tandem reactions of aromatic aldehydes, amines, and acetoacetic esters.

📜 SIMILAR VOLUMES

Highly efficient synthesis of homoallyli
Highly efficient synthesis of homoallylic alcohols and amines via allylation of aldehydes and imines catalyzed by ZrOCl2·8H2O in water
✍ Wei Shen; Li-Min Wang; Jian-Jun Feng; He Tian 📂 Article 📅 2008 🏛 Elsevier Science 🌐 French ⚖ 103 KB

The allylation of aldehydes and imines has efficiently been carried out by treatment with allyltributylstannane in the presence of a catalytic amount of ZrOCl 2 Á8H 2 O in water to form the corresponding homoallylic alcohols and amines, respectively, in high yields.

ChemInform Abstract: A Mild, Efficient a
ChemInform Abstract: A Mild, Efficient and One-Pot Synthesis of 2-Substituted Benzimidazoles by ZrOCl2×8H2O Catalyzed Ring Closure Reaction.
✍ Ch. Sanjeeva Reddy; A. Nagaraj 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

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