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Synthesis of substituted chiral piperazinones as building blocks for peptidomimetics

โœ Scribed by Kolter, Thomas ;Dahl, Christina ;Giannis, Athanassios

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
533 KB
Volume
1995
Category
Article
ISSN
0947-3440

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โœฆ Synopsis

A new approach to 3,6-disubstituted chiral piperazinones 6a, b and ?a, b from D-glucosamine hydrochloride (1) or N-Z-Dglucosamine (8) and L-amino acid derivatives 2a, b or 9a, b is presented. Both final products and the intermediate pseudopeptides constitute valuable starting materials for the synthesis of peptidomimetics.

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