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Synthesis of substituted 4-aminothieno[2,3-d]-, 4-aminothieno[3,2-d]- and 4-aminothieno[3,4-d]pyrimidines

โœ Scribed by A. V. Zadorozhny


Book ID
118298151
Publisher
Springer US
Year
2012
Tongue
English
Weight
402 KB
Volume
48
Category
Article
ISSN
0009-3122

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New syntheses of 7-substituted-2-aminoth
โœ Philip E. Morris Jr.; Arthur J. Elliott; John A. Montgomery ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 406 KB

## Abstract In a recent publication, we have the described the synthesis of 7โ€substitutedโ€2โ€aminoโ€1,5โ€dihydroโ€4__H__โ€pyrrolo[3,2โ€__d__]pyrimidinโ€4โ€ones which are potent inhibitors of the enzyme Purine Nucleoside Phosphorylase from the corresponding 3โ€aminopyrroIeโ€2โ€carboxylate esters. A key step in