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Synthesis of Substituted 2-Amino-4-quinazolinones via ortho-Fluorobenzoyl Guanidines.

✍ Scribed by M. Jonathan Fray; John P. Mathias; Carly L. Nichols; Yvonne M. Po-Ba; Hayley Snow

Publisher
John Wiley and Sons
Year
2006
Weight
17 KB
Volume
37
Category
Article
ISSN
0931-7597

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Convenient synthesis of some 2-substituted 4(3H)-quinazolinone derivatives
✍ I. Philipova; G. Dobrikov; K. Krumova; J. Kaneti πŸ“‚ Article πŸ“… 2006 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 125 KB

## Abstract magnified image A series of 2‐substituted‐4(3__H__)‐quinazolinones **13‐20** has been synthesized in good yields using the reaction of double lithiated 2‐methylquinazolinone‐4 with a variety of aromatic aldehydes. They have been easily transformed in high yields into the corresponding