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Synthesis of Substituted 1,2-Dihydroisoquinolines Through the Reaction of Isoquinoline and Dimethyl Acetylenedicarboxylate in the Presence of Amides.

โœ Scribed by Issa Yavari; Majid Ghazanfarpour-Darjani; Maryam Sabbaghan; Zinatossadat Hossaini


Publisher
John Wiley and Sons
Year
2007
Weight
21 KB
Volume
38
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis of 1,2-Di
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Synthesis of 1,2-Dihydroisoquinolines by the Reaction of Isoquinoline with Allyltributyltin or Silyl Enol Ethers in the Presence of N-Acylating Agents. -Isoquinolines (I) react with allyltributyltin or silyl enol ethers (V) in the presence of acylating agents (III) to give the 1,2-adducts (IV) and