Synthesis of substituted 1-benzyl-2,4,6-triphenyl-2,3-dihydro-pyrazolo [3,4-b] [1,4]diazepines
โ Scribed by Braulio Insuasty; Ricaurte Rodriguez; Jairo Quiroga; Roberto Martinez; Enrique Angeles
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1997
- Tongue
- English
- Weight
- 210 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
The acid catalyzed condensation of 4,5โdiaminopyrazoles and chalcones gave the hitherto unknown 1โbenzylโ2,4,6โtriphenylโ2,3โdihydropyrazolo[3,4โb][1,4]diazepines derivatives. The structure of all products was supported by ir, ^1^H and ^13^Cโnmr and mass spectra.
๐ SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
A facile approach to pyrazolo [4,3-e][1,4] diazepin-5,8-diones andpyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepin-5,10-diones is reported. Strategy involved the utility of ฮฑ-amino acid as a three-atom segment in the construction of diazepine skeleton on the preformed pyrazole ring.
## Abstract The synthetic pathway leading to 5,6โdihydroโ4__H__โfuro[3,2โ__f__]pyrrolo[1,2โ__a__][1,4]diazepines is described in four steps starting from ฮฑโbromophenones __via__ 2โaminoโ3โfuronitriles.