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Synthesis of stereoselectively labelled citric acids transformable into chiral acetic acids

✍ Scribed by Brand�nge, Svante; Dahlman, Olof


Book ID
120562714
Publisher
The Royal Society of Chemistry
Year
1983
Tongue
English
Weight
224 KB
Volume
22
Category
Article
ISSN
0022-4936

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Synthesis of chiral acetic acids by a si
✍ Peter F. Leadlay; Shaun Greer 📂 Article 📅 1982 🏛 Elsevier Science 🌐 English ⚖ 335 KB

A simple procedure for the synthesis of chiral acetic acids has been developed. The key step is an enzymatic exchange reaction which introduces 'H from 'H-labeled water into ethane I ,2diol. The method involves no resolution of racemic intermediates and the products are of high specific radioactivit