✦ LIBER ✦

Synthesis of stereoisomerically pube (E)-1,5-diyn-3-enes and (E)-1-bromo-3-yn-1-enes by diastereoselective palladium-catalyzed cross-coupling reaction of 1-alkynylzinc chlorides with a stereoisomeric mixture of 1,2-dibromoethylene.

✍ Scribed by Adriano Carpita; Renzo Rossi

Publisher: Elsevier Science
Year: 1986
Tongue: French
Weight: 200 KB
Volume: 27
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)94272-2

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✦ Synopsis

In the stereospecific palladiwn-catalyzed cross coupling reaction of I-alkynytzinc chlorides,(E)-1.2-dibromoethylene reacts preferentially in the presence of (ZI-1,2-dibmmoethylene.Rwiucts of di-or mono-substitution can be obtained according to the ratio of reagents.

📜 SIMILAR VOLUMES

Diastereoselective synthesis of (E)-1-tr

Diastereoselective synthesis of (E)-1-trimethylsilyl-3-en-1-ynes by palladium-catalyzed cross-coupling reaction between trimethylsilylethynylzinc chloride and stereoisomeric mixtures of 1-bromo-1-alkenes

✍ Bianca Patrizia Andreini; Adriano Carpita; Renzo Rossi 📂 Article 📅 1986 🏛 Elsevier Science 🌐 French ⚖ 132 KB

Swnmary: In the stereospecific pallad&m-cata2yzed cross-coupling reaction of trimethytsilylethynylzinc chloride, (El-I-bromo-I-a2kenes react preferentially in the presence of the cowespending (Z)-stereoisomers.