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Synthesis of Spirocyclic Pyrrolizidineoxyindoles with a Furotropylidene Fragment by 1,3-Dipolar Cycloaddition

โœ Scribed by Tkachuk, A. V.; Kurbatov, S. V.; Burov, O. N.; Kletskii, M. E.; Morozov, P. G.; Minkin, V. I.


Book ID
121659987
Publisher
Springer US
Year
2014
Tongue
English
Weight
506 KB
Volume
50
Category
Article
ISSN
0009-3122

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A convergent synthesis of substituted py
โœ George A. Kraus; Jon O. Nagy ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 184 KB

Thiazolium ylids 2a and 2b are converted to 4 in 3 steps. Summary: The 1,3-dipolar cycloaddition of azomethine ylids with activated alkenes constitutes an effective synthetic method for certain pyrrolidines. 1 However, the reaction is rather limited in that R and R' are invariably aryl substituents