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Microscale Synthesis of a Diphenylisoxazoline by a 1,3-Dipolar Cycloaddition

โœ Scribed by Martin, William B.; Kateley, Laura J.; Wiser, Dawn C.; Brummond, Catherine A.


Book ID
111901560
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
167 KB
Volume
79
Category
Article
ISSN
0021-9584

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A convergent synthesis of substituted py
โœ George A. Kraus; Jon O. Nagy ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 184 KB

Thiazolium ylids 2a and 2b are converted to 4 in 3 steps. Summary: The 1,3-dipolar cycloaddition of azomethine ylids with activated alkenes constitutes an effective synthetic method for certain pyrrolidines. 1 However, the reaction is rather limited in that R and R' are invariably aryl substituents