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Synthesis of Spiro Diphosphines and Their Application in Asymmetric Hydrogenation of Ketones

✍ Scribed by Xie, Jian-Hua; Wang, Li-Xin; Fu, Yu; Zhu, Shuo-Fei; Fan, Bao-Min; Duan, Hai-Feng; Zhou, Qi-Lin


Book ID
120548882
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
49 KB
Volume
125
Category
Article
ISSN
0002-7863

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Synthesis of novel chiral Schiff bases a
✍ Zhongqiang Zhou; Yongjun Bian πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 100 KB

## Abstract Novel chiral Schiff bases were synthesized from (+)‐camphor, and their application to asymmetric transfer hydrogenation of prochiral ketones is described. The asymmetric transfer hydrogenation reaction could afford excellent conversion rates (up to 97.3%) and up to 27.3% enantiomeric ex