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Synthesis of spacer-arm, lipid, and ethyl glycosides of the terminal trisaccharide [α-d-Gal-(1→4)-β-d-Gal-(1→4)-β-d-GlcNAc] portion of the blood-group P1 antigen: Preparation of neoglycoproteins

✍ Scribed by Jan Dahmén; Torbjörn Frejd; Göran Magnusson; Ghazi Noori; Anne-Sofie Carlström


Book ID
107725468
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
640 KB
Volume
129
Category
Article
ISSN
0008-6215

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2-bromoethyl glycosides in glycoside syn
✍ Jan Dahmén; Torbjörn Frejd; Göran Magnusson; Ghazi Noori; Anne-Sofie Carlström 📂 Article 📅 1984 🏛 Elsevier Science 🌐 English ⚖ 808 KB

The applicability of 2-bromoethyl glycosides in carbohydrate synthesis is demonstrated by the synthesis of glycosides of a-L-Fuc-(1+2)-D-Gal and /?-D-Gal-(1+4)-D-GlcNAc. The bromoethyl aglycon was transformed into the methoxycarbonylethylthioethyl spacer, which allowed coupling of the sugars to prot