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Synthesis of some novel imidazolidine derivatives and their metal complexes with biological and antitumor activity

✍ Scribed by Shaya Y. Al-Raqa; Ahmed M. Sh. ElSharief; Saied M. E. Khalil; Abdulkhaliq M. Al-Amri

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
279 KB
Volume
17
Category
Article
ISSN
1042-7163

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✦ Synopsis

Abstract

Halogenated imidazo(pyrazine,[1,4]diazocine and quinoxaline), 9,10‐anthraquinone‐ [6,7‐e], phenanthroline[5,6‐e] {imidazo[4,5‐b]pyrazine}, and naphtho[1,8‐ef]imidazo[4,5‐b][1,4] diazipen were obtained through interaction of imidazolidineiminothiones with the corresponding diamino compounds. Imidazo[4,5‐e] triazine and pyrrolo[2,3‐d]imidazole were prepared when the iminothiones were reacted with thiocarbohydrazide and with ethylphenyl acetate, separately. Some of the synthesized compounds exhibited better biological and antitumor activities. Β© 2006 Wiley Periodicals, Inc. Heteroatom Chem 17:634–647, 2006; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20244

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