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Synthesis of some novel 3,7-dimethyl-4H-pyrazolo[5,1-c][1,2,4]triazin-4-ones
✍ Scribed by Ahmed A. El-Barbary; Mahmoud A. El-Badawi; Yasser M. Loksha
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2001
- Tongue
- English
- Weight
- 66 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
Some novel 3,7‐dimethyl‐6__H__‐pyrazolo[5,1‐c][1,2,4]triazin‐4‐ones were prepared (3a‐g). Compounds 3a,b were treated with hydrazines to afford various products 7a,b, 8a,b, 9 and lla,b depending on the type of hydrazine derivative and reaction conditions. The benzoyloxyimino‐pyrazolo[5,1‐c][1,2,4]triazines (13a,b) were synthesized by refluxing of compounds 3a,b with hydroxylamine hydrochloride to afford the corresponding oxime derivatives followed by treatment with benzoyl chloride.
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract magnified image __E__‐3‐(__N,N__‐Dimethylamino)‐1‐(3‐methylthiazolo[3,2‐__a__]benzimidazol‐2‐yl)prop‐2‐en‐1‐one (**2**) was synthesized by the reaction of 1‐(3‐methylthiazolo[3,2‐__a__]benzimidazol‐2‐yl)ethanone (**1**) with dimethylformamide‐dimethylacetal. The reaction of **2** with