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Synthesis of some new substituted ethanone hydrazones containing 1H-1,2,4-triazole and thiazole

✍ Scribed by Fang-Ming Liu; Ya-Dong Sun; Zheng-Feng Xie


Publisher
Journal of Heterocyclic Chemistry
Year
2005
Tongue
English
Weight
62 KB
Volume
42
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

Three new thiosemicarbazones have been synthesized by condensation reaction of 2‐bromo‐1‐arylethanones with thiosemicarbazide, which reacted with various 2‐bromo‐1‐arylethanones in ethanol under refluxing to give a series of substituted ethanone hydrazone derivatives. Their structures were confirmed by elemental analysis, IR, ^1^H NMR, and MS spectra.


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Synthesis of 1,2,4-triazole and thiazole
✍ Liang-Fu Huang; Jang-Woo Kim; Ludwig Bauer; George Doss πŸ“‚ Article πŸ“… 1997 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 625 KB

## Abstract The synthesis of 1,2,4‐triazole and thiazole analogs of ketoconazole is described in which one of the Ξ± azole ring carbons is linked to C‐2 of the ketal by means of a three methylene tether. Lithiation of 1‐methyl‐1,2,4‐triazole and thiazole and subsequent alkylation with 2‐(2,4‐dichlor