## Abstract Three new thiosemicarbazones have been synthesized by condensation reaction of 2βbromoβ1βarylethanones with thiosemicarbazide, which reacted with various 2βbromoβ1βarylethanones in ethanol under refluxing to give a series of substituted ethanone hydrazone derivatives. Their structures w
β¦ LIBER β¦
Synthesis of Some New Substituted Ethanone Hydrazones Containing 1H-1,2,4-Triazole and Thiazole.
β Scribed by Ya-Dong Sun; Fang-Ming Liu; Zheng-Feng Xie
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 18 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The synthesis of 1,2,4βtriazole and thiazole analogs of ketoconazole is described in which one of the Ξ± azole ring carbons is linked to Cβ2 of the ketal by means of a three methylene tether. Lithiation of 1βmethylβ1,2,4βtriazole and thiazole and subsequent alkylation with 2β(2,4βdichlor