Synthesis of some 7-substituted-2,4,8(1H,3H,7H)pyrimido[5,4-d]pyrimidinetriones
โ Scribed by William Pendergast; William R. Hall
- Book ID
- 112128355
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1986
- Tongue
- English
- Weight
- 205 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0022-152X
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๐ SIMILAR VOLUMES
An improved synthesis of 3-(substituted)pyrimido[4,5-c]pyridazine-5,7(1H,6H)-diones, a known subclass of 4-deazatoxoflavins, is reported. The approach involves treatment of 3-methyl-6-(1-methylhydrazinyl)uracil with representative phenyl and alkyl glyoxal monohydrates, which in turn are obtained by
The asymmetric unit of the title compound, C 19 H 16 FN 5 O 4 , contains two independent molecules. The dihedral angles between the main planes and the fluorophenyl rings in the two molecules are 83.24 (5) and 71.76 (4) . Weakstacking interactions may be effective in the stabilization of the crystal