Synthesis of some 6-chloro-3,7-dihydroxy-.DELTA.5-pregnene derivatives
โ Scribed by Le Mahieu, Ronald A.; Boris, Alfred; Carson, M.; Kierstead, Richard W.
- Book ID
- 126430513
- Publisher
- American Chemical Society
- Year
- 1971
- Tongue
- English
- Weight
- 554 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0022-2623
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๐ SIMILAR VOLUMES
OF the twenty-one known natural isoflavones,' three, tectorigenin, irigenin, and caviunin, are derivatives of 5,7-dihydroxy-6-methoqyisoflevone. This particular orientation of substituents makes a direct synthesis difficult, but a method, which we believe to be general, for the synthesis of such iso
So far one has only succeded in synthetising 5.7~dihydroxy-6-methoxyflavonea bearing not more than one substituent on the phenyl side Aain /B-ring/ l-9. b tried to solve this problem by alkaline ring isomerization 10-12.