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Synthesis of somatostatin by breast cancer cells and their inhibition by exogenous somatostatin and sandostatin

โœ Scribed by Nelson, J; Cremin, M; Murphy, RF

Book ID
109836134
Publisher
Nature Publishing Group
Year
1989
Tongue
English
Weight
771 KB
Volume
59
Category
Article
ISSN
0007-0920

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Addition of ATP (>0.1 mM) to cultures of human breast cancer T47D cells resulted in an inhibition of cell proliferation. The inhibition was found to be specific for ATP, and dependent on its concentration. Growth inhibition continued for at least three days, although ATP and its hydrolysis products