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Synthesis of Small Molecules Targeting Multiple DNA Structures using Click Chemistry

✍ Scribed by Dr. Lesley A. Howell; Dr. Richard A. Bowater; Dr. Maria A. O'Connell; Anthony P. Reszka; Prof. Stephen Neidle; Prof. Mark Searcey


Book ID
112066696
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
690 KB
Volume
7
Category
Article
ISSN
1860-7179

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πŸ“œ SIMILAR VOLUMES


Solid-phase synthesis of small molecule
✍ John Nielsen; Flemming R. Jensen πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 French βš– 196 KB

The first synthesis of a combinatorial library using double combinatorial chemistry is presented. Coupling of unprotected Fmoc-tyrosine to the solid support was followed by Mitsunobu O-alkylation. Introduction of a diacid linker yields a system in which the double combinatorial step can be demonstra