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Synthesis of semicarbazones and thiosemicarbazones of 1-(2-benzothiazolon-3-yl) propanones

✍ Scribed by A. Ts. Antonova; D. Simov; V. B. Kalcheva

Publisher
Springer US
Year
1989
Tongue
English
Weight
220 KB
Volume
25
Category
Article
ISSN
0009-3122

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✦ Synopsis

Semi-and thiosemicarbazones were synthesized by the reaction of l-(2-benzothiazolon-3-yl)propanones with semi-and thiosemicarbazide, These compounds are more active in stimulating plant growth than the starting propanones.

Systems that contain two potentially biologically active segments usually display valuable biological activity.

In the present work we discuss the synthesis of such types of compounds, viz., the semicarbazones and the thiosemicarbazones, which usually show pronounced biological properties [i, 2]; they are derived from the benzothiazolonyl ketones, which are knownfor their physiological activity [3,4]. Indeed biological tests have shown that activ ity of these compounds in regulating plant growth is stronger [5] than that of the starting ketones [6].

Compounds (II) and (III) were obtained by the reaction of equimolar amounts of 1-(2benzothiazolonyl) propanones (I) and semi-or thiosemicarbazide in 68-97% yield (Table i).

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