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Synthesis of santonin related compounds

✍ Scribed by Sadao Tsuboi; Koichi Shinhama; Akira Takeda


Book ID
112128880
Publisher
Journal of Heterocyclic Chemistry
Year
1988
Tongue
English
Weight
175 KB
Volume
25
Category
Article
ISSN
0022-152X

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AbstractÐThis article reports on the transformation of santonin into two C 10 -epimeric 3-oxa-guaianolides which are 8-deoxyderivatives of several natural 3-oxaguaianolides isolated from Achillea species. The synthesis involved the photochemical rearrangement of the eudesmane skeleton into a guaiane