Synthesis of S(+) and R(-)-3-(2-aminopropyl)indole from ethyl-D- and L-tryptophanate
✍ Scribed by David B. Repke; Wilfred J. Ferguson
- Book ID
- 112123810
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1976
- Tongue
- English
- Weight
- 243 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
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## Abstract α‐Deuterated tryptophan was prepared either by exchange of the α‐hydrogen of tryptophan or by hydrolysis and decarboxylation of ethyl 2‐formamido‐2‐carbethoxy‐3‐indole propionate, followed by treatment with CH~3~COO^2^H. α,β‐Dideuterated tryptophan was in turn synthetized from ethyl‐α‐a
## Abstract Labeled 1‐tryptophan is converted to indole‐3‐acetamide and then to indole‐3‐acetic acid by enzymes from __Pseudomonas savastanoi__. Labeled indole‐3‐acetic acid can be converted to indole‐3‐acetyl‐1‐__0__‐β‐D‐glucose and to indole‐3‐acetyl‐__myo__‐inositol by enzymes from kernels of __