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Synthesis of Rimocidinolide Methyl Ester (I), the Aglycone of (+)-Rimocidin.

โœ Scribed by Garrick K. Packard; Yueqing Hu; Andrea Vescovi; Scott D. Rychnovsky


Publisher
John Wiley and Sons
Year
2004
Weight
61 KB
Volume
35
Category
Article
ISSN
0931-7597

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Synthesis of the macrolide antibiotic A2
โœ T.A. Hase; E.-L. Nylund ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 210 KB

The total synthesis of the title compound (1) is reported. The isolation and structure elucidation of the 16-membered lactone antibiotic A2677lB (1) from PeniciZZium turbatum (Westling) was recently reportedl. The compound shows optical activity but its absolute (and relative) stereostructure is u