𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of racemiry, (+) and (-) N-(methyl-11C) nomifensine, a ligand for evaluation of monoamine reuptake sites by PET

✍ Scribed by J. Ulin; A.D. Gee; P. Malmborg; B. Långström

Publisher
John Wiley and Sons
Year
1989
Tongue
French
Weight
134 KB
Volume
26
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis of a radiotracer for studying
Synthesis of a radiotracer for studying dopamine uptake sites in vivo using PET: 2β-carbomethoxy-3β-(4-fluorophenyl)-[N-11C-methyl]tropane ([11C]CFT or [11C]WIN-35,428)
✍ Robert F. Dannals; John L. Neumeyer; Richard A. Milius; Hayden T. Ravert; Alan A 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 French ⚖ 320 KB

## Abstract 2β‐Carbomethoxy‐3β‐(4‐fluorophenyl)‐[N‐^11^C‐methyl]tropane, a potent inhibitor of dopamine transport, was prepared by N‐methylation of the appropriate nor‐methyl precursor in DMF with [^11^C]iodomethane. After derivatization of unreacted precursor with a long chain acyl halide, the rad

Synthesis and PET evaluation of (R)-[S-m
Synthesis and PET evaluation of (R)-[S-methyl-11C]thionisoxetine, a candidate radioligand for imaging brain norepinephrine transporters
✍ Magnus Schou; Victor W. Pike; Andrea Varrone; Balázs Gulyás; Lars Farde; Christe 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 164 KB

## Abstract __Introduction:__ (__R__)‐3‐(2‐(methylthio)phenoxy)‐__N__‐methyl‐3‐phenylpropan‐1‐amine [(__R__)–thionisoxetine; **1**] is a potent inhibitor of the norepinephrine transporter (NET). We aimed to label **1** with carbon‐11 (__t__~1/2~ = 20.4 min) for evaluation as a radioligand for imagi

Synthesis of (R)-(–)-2-Fluoronorapomorph
Synthesis of (R)-(–)-2-Fluoronorapomorphine — A Precursor for the Synthesis of (R)-(–)-2-Fluoro-N-[11C]propylnorapomorphine for Evaluation as a Dopamine D2 Agonist Ligand for PET Investigations
✍ Kåre Søndergaard; Jesper Langgaard Kristensen; Nic Gillings; Mikael Begtrup 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 138 KB

## Abstract 2‐Fluoronorapomorphine, the PET labelling precursor to 2‐fluoro‐__N__‐[^11^C]propylnorapomorphine, was prepared in 13 steps from codeine in a total yield of 10 %. Codeine was converted in four steps into __N__‐benzylnorcodeine which was oxidised by using the Swern protocol. Subsequent a