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Synthesis of (R)-cyclohexylmethyl-p-styrylphosphine and the preparation of polymer-bound optically active phosphines

✍ Scribed by Sybert, P. D.; Bertelo, C.; Bigelow, W. B.; Varaprath, S.; Stille, J. K.


Book ID
127320970
Publisher
American Chemical Society
Year
1981
Tongue
English
Weight
711 KB
Volume
14
Category
Article
ISSN
0024-9297

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Synthesis of (R)- and (S)-5-(Hydroxymeth
✍ Erwin G. J. C. Warmerdam; Johannes Brussee; Arne van der Gen; Chris G. Kruse πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 German βš– 332 KB

## Abstract The (__R__)‐ and (__S__)‐5‐(hydroxymethyl)‐3‐isopropyloxazolidin‐2‐ones, ((__R__)‐ and (__S__)‐2, resp.), pivotal intermediates in the preparation of optically active β‐blockers, were synthesized using (__R,E__)‐2‐hydroxypent‐3‐enenitrile (1) as the chiral starting material. In the synt