Recently, Palmer and Russell (1) have reported that k-methylcinnoline afforded k-methylcinnol~ne 1,2-dioxide by the action of hydrogen peroxide and acetic acid, and the structure of the latter was elucidated by n.m.r., mass, W, IR spectrometry. We have also independently succeeded in the synthesis o
Synthesis of pyrrolo[1,2-b]cinnolines
✍ Scribed by R. Richard L. Hamer; Danette Sekerak; Richard C. Effland; Joseph T. Klein
- Book ID
- 112128967
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1988
- Tongue
- English
- Weight
- 286 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0022-152X
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## Abstract A modular synthesis of selectively‐substituted pyrrolo[2,1‐__b__]thiazoles (Δ^6^ isomeric form) has been implemented, involving a distinctive bicyclization reaction of a mucobromic acid derivative followed by a Suzuki‐Miyaura coupling. A novel process of Δ^6^ to Δ^7^ isomerization of th
Diethyl Pyrrolo[1,2‐__b__]cinnoline‐6,8‐dicarboxylate, a Product of an Anomalous Vilsmeier Reaction A byproduct of the Vilsmeier reaction of 1 has been shown by X‐ray structure determination to be the pyrrolo[1,2‐__b__]cinnoline 3. Informations concerning the mechanism of formation of 3 have been o