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Synthesis of pyrrolo[1,2-a]pyrazines and pyrazino[1,2-a]indoles by Curtius reaction in Morita–Baylis–Hillman derivatives

✍ Scribed by Maloy Nayak; Garima Pandey; Sanjay Batra

Book ID
113928829
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
374 KB
Volume
67
Category
Article
ISSN
0040-4020

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📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of Pyrrol
ChemInform Abstract: Synthesis of Pyrrolo[1,2-a]pyrazines and Pyrazino[1,2-a]indoles by Curtius Reaction in Morita—Baylis—Hillman Derivatives.
✍ Maloy Nayak; Garima Pandey; Sanjay Batra 📂 Article 📅 2012 🏛 John Wiley and Sons ⚖ 43 KB

## Abstract Key feature of the synthesis of title pyrrolopyrazine scaffolds is the Curtius reaction of formylpyrrolyl‐substituted acids to generate an isocyanate, which is directly cyclized in the presence of formic acid [cf.