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Synthesis of Pyrrole-3-carboxylic Acids

✍ Scribed by RAPOPORT, HENRY; WILLSON, CLYDE D.


Book ID
126451533
Publisher
American Chemical Society
Year
1961
Tongue
English
Weight
362 KB
Volume
26
Category
Article
ISSN
0022-3263

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Synthesis of isocoumarin-3-carboxylic ac
✍ C. Ribbens; C. van der Stelt; W. Th. Nauta πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 206 KB

## Abstract 2‐Carboxyphenylpyruvic acid and its derivatives with substituents in the phenyl nucleus can be prepared via a modified azlactone synthesis. These phenylpyruvic acids display a spontaneous ring closure into the corresponding isocoumarin carboxylic acids.