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Synthesis of pyrido[1,2-a]benzimidazoles by photo-stimulated C–N bond formation via SRN1 reactions

✍ Scribed by Barolo, Silvia M.; Wang, You; Rossi, Roberto A.; Cuny, Gregory D.


Book ID
120360855
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
906 KB
Volume
69
Category
Article
ISSN
0040-4020

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The reaction of N-carboxymethylpyrido[1,2-a]-and pyridazino[1,6-a]benzimidazolium salts with thionyl chloride resulted in an N-C bond fission, yielding the corresponding pyrido[ 1,2-a]and pyridazino[1,6-a]benzimidazoles. A similar dealkylation process was observed when analogous N-propargylic deriva