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Synthesis of pyrazolo[1,5-a]-, 1,2,4-triazolo[1,5-a]- and imidazo[1,2-a]pyrimidines related to zaleplon, a new drug for the treatment of insomnia

✍ Scribed by Carlo Mustazza; Maria Rosaria Del Giudice; Anna Borioni; Franco Gatta

Publisher
Journal of Heterocyclic Chemistry
Year
2001
Tongue
English
Weight
119 KB
Volume
38
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

This paper describes the preparation of some pyrazolo[1,5‐a]‐, 1,2,4‐triazolo[1,5‐a]‐ and imidazo[1,2‐a]‐pyrimidines substituted on the pyrimidine moiety by a 4‐[(N‐acetyl‐N‐ethyl)amino]phenyl group. A new synthesis of related benzo[h]pyrazolo[1,5‐a]‐, benzo[h]pyrazolo[5,1‐b]‐ and benzo[h]1,2,4‐triazolo[1,5‐a]‐quinazolines is also reported.

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