๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Synthesis of Protein Farnesyltransferase and Protein Geranylgeranyltransferase Inhibitors: Rapid Access to Chaetomellic Acid A and Its Analogues

โœ Scribed by Ratemi, Elaref S.; Dolence, Julia M.; Poulter, C. Dale; Vederas, John C.


Book ID
127170331
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
185 KB
Volume
61
Category
Article
ISSN
0022-3263

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Design and synthesis of a protein:Farnes
โœ Herman S Overkleeft; Steven H.L Verhelst; Elsbet Pieterman; Nico J Meeuwenoord; ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 268 KB

The synthesis of four partially deoxygenated gluconic amino acids from fully acetylated D-glucal is described. Replacement of the central AA dipeptide in the CAAX tetrapeptide corresponding to the C-terminus of K-Ras p21 by one of these sugar amino acid building blocks led to a novel protein:farnesy

ChemInform Abstract: Stereospecific Synt
โœ M. TSUDA; Y. MURAOKA; T. TAKEUCHI; R. SEKIZAWA; K. UMEZAWA ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 30 KB ๐Ÿ‘ 2 views

Stereospecific Synthesis of a Novel Farnesyl Protein Transferase Inhibitor, Valinoctin A and Its Analogues. -The valinoctin A analogue (VIII), prepared via Curtius rearrangement of an intermediate azide, shows essentially the same inhibitory activity as the parent compound. -