𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of prostaglandin analogs by novel 1,4 addition reactions

✍ Scribed by Raphael Pappo; Paul W. Collins

Publisher
Elsevier Science
Year
1972
Tongue
French
Weight
174 KB
Volume
13
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

In 1969 ve initiated a progrem to study the application of 1,4 addition reactions to the synthesis of prOSteglEt&inB. Recent publications 192 corroborating saw of our work have prompted us to report the preliminary results of our efforts.

📜 SIMILAR VOLUMES

Organopalladium approaches to prostaglan
Organopalladium approaches to prostaglandins. 7.1 : Synthesis of prostaglandin endoperoxide analogs by vinylpalladation of norbornene
✍ R.C. Larock; M.H. Hsu; K. Narayanan 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 453 KB

Vinylpalladation of norbornene using vinylmercurial 5 and Li2PdC14 affords the corresponding cis-exo adduct 6 which can be directly carbonylated to methyl ester 7 in 60% overall yield. Reduction to aldehyde 9 and subsequent chain elaboration provides the new prostaglandin endoperoxide analog 12. Epi

Synthesis of new monomers by addition re
Synthesis of new monomers by addition reactions of diethylamine to 1,4-divinylbenzene catalyzed by lithium diethylamide
✍ Tsuruta, Teiji ;Narita, Tadashi ;Nitadori, Yoshiaki ;Irie, Tadashi 📂 Article 📅 1976 🏛 Wiley (John Wiley & Sons) ⚖ 295 KB

## Abstract Addition reactions of diethylamine onto 1,4‐divinylbenzene (DVB) catalyzed by lithium diethylamide were examined to find a synthetic route to a group of new monomers possessing dialkylamino substituents, which is expected to be a starting material for biomedical polymers such as ionic p

Synthesis and Addition Reactions of 1,3-
Synthesis and Addition Reactions of 1,3-Thiazole-5(4H)-thione Oxides
✍ Junxing Shi; Peter Tromm; Heinz Heimgartner 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 German ⚖ 584 KB

## Abstract 1,3‐Thiazole‐5(4__H__)‐thione oxides 2 were prepared by oxidation of the corresponding 1,3‐thiazole‐5(4__H__)‐thiones 1 with __m__‐chloroperbenzoic acid (__Table 1__). Addition reactions of 2 with organolithium and __Grignard__ reagents yielded 4,5‐dihydro‐4,4‐dimethyl‐1,3‐thiazol‐5‐yl

The synthesis of 1-aminodihydroisoquinol
The synthesis of 1-aminodihydroisoquinolines by an imine addition-cyclisation reaction
✍ Haydn Beaton; Peter Hamley; Alan C. Tinker 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 201 KB

A variety of l-amino-3,4-dihydroisoquinolines substituted at the 3-position and related thienopyridines were prepared by lithiation of ortho-methyl aromatic nitriles, addition to Ntrimethylsilylimines and spontaneous cyclisation.